Preheat oven to 350 degrees.
Gently crumble ground beef in a large bowl, breaking up into small pieces. Add remaining meatloaf ingredients to the bowl and gently combine, being careful not to overwork the meat.
Mix all sauce ingredients together and spread half of the sauce along the bottom and sides of a bread loaf pan.
Add meatloaf to a loaf pan and press firmly into a loaf shape.
Liberally paint remaining sauce over the loaf.
Place meatloaf in the oven and bake for 1 hour 10 minutes, or until the internal temperature reads 165 degrees.
Let rest for five minutes, then slice and serve.