Trim excess fat, leaving about ¼-inch fat cap on one side.
Remove any silverskin or hard fat that won’t render during cooking.
Pat the brisket dry with paper towels.
Rub a light coating of mustard on all sides (optional).
In a small bowl, mix salt, pepper, garlic powder, and smoked paprika.
Rub the seasoning generously and evenly all over the brisket.
(Optional) Drizzle Worcestershire and/or liquid smoke on both sides for flavor.
Place the seasoned brisket on a baking sheet or rack.
Refrigerate uncovered for at least 4 hours or overnight.
Bring to room temperature for 1 hour before cooking.
Preheat oven to 250°F (121°C).
Place brisket fat-side up on a wire rack set in a roasting pan or on a foil-lined baking sheet.
Roast uncovered for 4–6 hours, depending on size, until internal temp reaches 165°F (74°C).
Wrap the brisket in butcher paper or foil.
Return to oven and continue roasting until internal temp reaches 200–205°F (93–96°C). This can take another 2–3 hours.
Remove from oven and let it rest wrapped for 1 hour before slicing.
Unwrap and place on a cutting board.
Slice against the grain for maximum tenderness.
Serve with your favorite BBQ sides.
