Prepare oven: Preheat the oven to 350°F.
Crush pretzels and crackers: Heat butter in a microwave-safe bowl until completely melted. Crush pretzels and graham crackers into small pieces.
Mix pie filling: Combine all filling ingredients (chocolate chips, pretzels, graham crackers, coconut, pecans, caramel bits, butter, and sweetened condensed milk) in a large bowl until well blended.
Bake pie: Pour the entire filling into a frozen pie crust. Bake in the oven for 35 minutes or until the pie is set and the top is golden brown. Let pie cool for 30 minutes before cutting and serving.
