Preheat your oven to 350°F (175°C).
In a large bowl, combine the ground sausage, shredded cheddar cheese, baking mix, milk, jalapeño, smoked paprika, garlic powder, and onion powder. Mix until well combined.
Roll the mixture into 1-inch balls and place them on a baking sheet lined with parchment paper.
Bake for 20-25 minutes until golden brown and cooked through.
