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Whisk together honey, brown sugar, Dijon mustard, mayonnaise, apple cider vinegar, and salt and pepper.
Brush about half of the glaze on a 10-pound ham, making sure to get in between the slices.
Cover the ham with foil and bake in the oven for 60 to 75 minutes at 325°F, brushing with more glaze every 20 minutes.
With 15 to 20 minutes cooking time to go, remove the foil and brush on the remaining glaze.
Increase the oven temperature to 400°F and continue baking until the exterior is glossy, deeply golden, and lightly caramelized.