Preheat oven to 375°F.
Lightly grease a 9x13-inch baking dish.
Place the chicken breasts in the prepared baking dish.
In a medium bowl, combine the mayonnaise, Parmesan cheese, garlic powder, onion powder, paprika, salt, and pepper.
Spread the mixture evenly over the chicken breasts.
Bake uncovered for 40–45 minutes, or until the chicken reaches an internal temperature of 165°F.
Allow the chicken to rest for 5 minutes before serving.
Sprinkle with parsley if desired.
