For best results, apply to young plants in the late morning on a warm, sunny day with no rain forecast for at least 36 hours.

This works best on hardscapes, gravel areas, and trimmed lawns. In small amounts, it won't kill well-established plants: but use common sense. Avoid applying to garden beds or heavily onto landscaping unless you're confident in your conditions.

In dry climates with clay soils, even light use can be potent—both in stunting unwanted growth and making the soil less welcoming for desired plants. In contrast, wetter climates with fast-draining soils will need heavier or more frequent applications.

If you want to remove large quantities of sod cover with black plastic or fence chickens around it.

If you want to spot treat weeds- spraying a pesticide, however natural it may be, is treating only a symptom. "Weeds" are dynamic accumulators which thrive in poor soils, nature is trying to tell you to add fertilizer, because grasses have co-evolved with animals. Trying to kill these broad perennial "weeds" is just getting on an expensive, time consuming, soil sterilizing treadmill.

Vining plants like ivy will likely need multiple treatments and a stronger vinegar concentration. But honestly, you're better off pulling them by hand, using goats—or in extreme cases, pigs—then reseeding or planting afterward.

30% vinegar is strong. While its effects aren't cumulative (something LD50 tests don't fully capture), it can irritate your eyes and lungs. Use eye protection and consider a mask if you're spraying in enclosed or poorly ventilated areas.