In a mixing bowl, combine biscuit mix, shredded cheddar, milk, garlic powder, and parsley.
Stir until a soft, cohesive dough forms.
In another bowl, mix lump crab meat with cream cheese, mayonnaise, Old Bay, salt, and pepper.
Stir until smooth and evenly combined.
Pinch off a small piece of dough and flatten it gently in your hand.
Spoon 1–2 teaspoons of crab filling into the center.
Wrap the dough around the filling and pinch to seal tightly into a ball.
Place each stuffed dough ball on a lined baking sheet.
Bake at 375°F (190°C) for 15–18 minutes, or until golden brown.
Brush immediately with melted butter for extra flavor.