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Preheat the oven to 400 degrees F (204 degrees C). Pat the fish fillets dry with paper towels and place on a rimmed baking sheet.
In a small bowl, whisk together melted butter, olive oil, and lemon juice. Brush the butter mixture onto both sides of each fish fillet.
In a separate small bowl, stir together the paprika, garlic powder, salt and pepper. Season both sides liberally with the seasoning mixture.
Bake flounder in the oven for 12-15 minutes, until the fish flakes easily with a fork or reaches an internal temperature of 140 degrees F (60 degrees C).