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Preheat the oven to 375°F (190°C).
Lightly grease a baking dish and place the chicken breasts in a single layer.
In a mixing bowl, combine the mayonnaise, Parmesan cheese, garlic powder, onion powder, paprika, parsley, salt, and black pepper.
Spread the creamy mixture evenly over the top of each chicken breast.
Bake uncovered for 40–45 minutes, until the chicken is fully cooked and the topping is lightly golden.
Let the chicken rest for about 5 minutes before serving so the juices settle.
Garnish with a little fresh parsley if desired and serve warm.