Preheat oven to 375°F (190°C). Line a baking sheet with parchment paper or lightly grease it.
Mix mayonnaise, Parmesan cheese, Ranch seasoning mix, garlic powder, and onion powder in a bowl until smooth.
Coat each chicken tender in the mayo mixture, then dredge in crushed Ritz crackers, pressing to ensure coating sticks.
Arrange tenders on prepared baking sheet and bake for 20-25 minutes until golden and cooked through to 165°F internally.
