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Preheat oven to 350ºF. Lightly spray a 9x9-inch baking dish with cooking spray and set aside.
Combine chicken, cream cheese, cottage cheese, sour cream, garlic powder, onion powder, and cream of chicken soup. Spread into prepared pan.
Combine crushed crackers and butter, sprinkle over chicken mixture..
Bake uncovered 30 to 40 minutes.
Notes
Use a rotisserie chicken for quick prep of the cooked chicken.
You want the cream cheese to be very soft so it gets fully incorporated into the casserole. If you are short on time then soak unopened cream cheese in warm water for 15-20 mins
Can prepare through step 3 and refrigerate or freeze for later.
To bake after freezing, thaw completely and bake as directed above.
For a gluten-free dish, use gluten-free Cream of Chicken soup and crushed pork rinds instead of Ritz crackers.