Preheat your oven to 375°F (190°C). Line a baking sheet with parchment paper or a silicone baking mat.
In a large mixing bowl, combine the raw sausage, softened cream cheese, drained Rotel, shredded cheddar cheese, and Bisquick. Mix thoroughly with a spoon or your hands until well combined.
Roll the mixture into 1-inch balls and place them on the prepared baking sheet, spacing them about 1 inch apart.
Bake in the preheated oven for 20-25 minutes, or until the sausage balls are golden brown and cooked through.
Serve warm as a snack or appetizer. Pair with dipping sauces like ranch dressing or spicy mustard if desired.
Store any leftovers in an airtight container in the refrigerator for up to 3 days. Reheat in the oven or microwave before serving.
