Add the mayonnaise, yellow mustard, Dijon mustard, Worcestershire sauce, onion powder, garlic powder, smoked paprika, salt, and pepper to a bowl.
Whisk the ingredients together until smooth and creamy.
Taste and adjust seasoning as needed.
Cover and refrigerate until ready to serve.
Serve the sauce on the side to slather on ham, and save the leftovers for sandwiches.
