Preheat the oven: Set the oven to 350°F (175°C) and grease a standard loaf pan to prevent sticking.

Mix the dry ingredients: In a large bowl, whisk together the all-purpose flour, baking powder, baking soda, salt, garlic powder, oregano, and thyme to evenly distribute the leavening agents and spices.

Incorporate the cheeses: Add the shredded cheddar, mozzarella, and Parmesan to the dry mixture, tossing them gently so they are evenly coated with flour, which helps prevent clumping.

Prepare the wet ingredients: In a separate bowl, whisk together the buttermilk, melted butter, and eggs until smooth, ensuring the butter has cooled slightly to prevent cooking the eggs.

Combine wet and dry mixtures: Pour the wet ingredients into the dry ingredients and mix gently with a spatula or wooden spoon until just combined; avoid overmixing to keep the bread tender.

Transfer to the loaf pan: Spread the batter evenly into the greased loaf pan, smoothing the top to ensure even baking.

Bake the bread: Place the pan in the preheated oven and bake for 45 to 50 minutes, or until a toothpick inserted in the center comes out clean with no wet batter.

Cool before slicing: Let the bread cool in the pan for 10 minutes before transferring it to a wire rack to cool completely, allowing the flavors to settle and the texture to firm up.

Serve and enjoy: Slice and serve warm or at room temperature as a side dish, snack, or accompaniment to your favorite meal.