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Preheat oven to 375 degrees F.
Melt butter in a small bowl and set aside.
Crush crackers in a food processor or a Ziploc bag with a rolling pin, until they become fine crumbs.
Combine crushed crackers, Italian seasoning, garlic powder, salt and pepper in a separate mixing bowl.
Spray a 9x13-inch baking pan with nonstick cooking spray.
Dip each chicken breast in melted butter, coat completely in crumb mixture and place in prepared pan.
Bake for 25-30 minutes, or until cooked through.