Preheat oven to 400F. Spray a baking sheet with nonstick cooking spray.
In a small bowl, mix together the cream cheese and mustard until smooth.
Open the can of biscuits. On a work surface, lay out the biscuits and flatten to slightly larger than the normal size. Spread the cream cheese mixture evenly on each of the biscuits. Place 1-2 slices of deli ham on each biscuit, followed by equal amounts of cheese.
Fold the biscuits in half, enclosing the ham and cheese, forming a half moon shape. Pinch the edges together, or use a fork to seal the edges. Transfer to the prepared baking sheet.
Bake for 10-12 minutes, or until the biscuits are browned and cooked through.
