Combine dry snacks: Place the cereal, cheese crackers, pretzels and nuts into a large bowl.
Seasoning: Mix together the melted butter, Worcestershire sauce, seasoned salt, garlic powder, onion powder and cayenne. Slowly drizzle the butter mixture over the cereal, while tossing gently, to coat.
Bake: Preheat the oven 250°F. Transfer the Chex Mix onto two baking sheets, spreading it into an even layer. Bake for 1 hour, stirring every 20 minutes. Remove from oven and allow to cool before serving.
