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Preheat the oven to 350 degrees F (175 degrees C). Grease a loaf pan. Mix flour, sugar, baking powder, and salt in a large bowl.
Stir milk, oil, egg, and vanilla extract into flour mixture until just blended; gently fold blueberries into batter and pour into prepared loaf pan.
Bake in the preheated oven until a toothpick inserted into the center comes out clean, 60 to 70 minutes. Cool briefly on a wire rack before inverting carefully onto a serving plate or cooling rack. Let cool completely.