Preheat the oven to 375 degrees F and grease a standard muffin pan with nonstick spray.
Add the flour, wheat bran, baking powder, baking soda, salt, and cinnamon to a large bowl. Stir to combine gently.
Add the milk, eggs, butter, honey, applesauce, and vanilla and whisk gently to combine.
Stir in the blueberries (or raisins or chocolate chips). Divide the batter into the prepared muffin pan, using a heaping ¼ cup in each.
Bake for 14-16 minutes, or until a cake tester inserted into the center comes out clean. Transfer muffins to a wire rack to cool (at least a little) and serve slightly warm.
