Preheat the oven to 375°F and grease a 9×13-inch baking dish.
Blend cottage cheese until smooth. Mix with Alfredo sauce, onion powder, garlic powder, and salt.
Season chicken cubes generously. Heat olive oil over medium-high and brown chicken pieces until golden.
Spread broccoli evenly in the dish. Add chicken next. Scatter parmesan for structure and sharpness. Pour on the creamy Alfredo mixture. Finish with mozzarella so the top browns beautifully.
Bake 35 minutes. Broil briefly for a golden, bubbling finish.
