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Preheat the oven to 375°F.
Slice the bread in half through the middle and place it cut side up on a baking sheet. Drizzle both sides of the bread with olive oil and sprinkle with 1 tsp Italian seasoning.
Layer provolone cheese on the top piece of the bread and sprinkle with the remaining ¼ tsp Italian seasoning. Place the ham in a layer on the bottom piece of bread, followed by the pepperoni.
Bake for about 18 minutes, until the cheese is melted with deep golden brown spots and the bread is crisp and toasted.
While the sub is in the oven, toss the tomatoes, pepperoncinis, and iceberg lettuce generously in Italian dressing.
Layer the veggies on top of the ham and pepperoni and place the cheesy bread on top. Cut in six sections along a diagonal angle and enjoy!